Alterations of neutrophils function by tobacco products may play a
central role in the pathogen- esis of periodontal diseases and several
smoking related systemic diseases. The aim of the study was to assess a
response of peripheral blood neutrophils unstimulated and stimulated by
prodigiosan to smoking.
Materials and methods. The study included 17 smoking men that addressed for treatment of various odontological problems to out patient department of Kaunas University Clinic. The subjects were 22-43 years of age and systemic diseases free. All subjects answered to questions about smoking habits. To assess the response of neutrofils (unstimulated and stimulated by prodigiosan) to smoking the chemiliuminescence and nitroblue tetrazolium test were used to measure their oxidative metabolism.
Materials and methods. The study included 17 smoking men that addressed for treatment of various odontological problems to out patient department of Kaunas University Clinic. The subjects were 22-43 years of age and systemic diseases free. All subjects answered to questions about smoking habits. To assess the response of neutrofils (unstimulated and stimulated by prodigiosan) to smoking the chemiliuminescence and nitroblue tetrazolium test were used to measure their oxidative metabolism.
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