الخميس، 15 أغسطس 2013

General health of dentists. Literature review

1 0 Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1
General health of dentists. Literature review
Alina Puriene, Vilija Janulyte, Margarita Musteikyte, Ruta Bendinskaite
REVIEW
Stomatologija, Baltic Dental and Maxillofacial Journal, 9:10-20, 2007
*Institute of Odontology, Faculty of Medicine, Vilnius university,
Lithuania
Alina Puriene* – D.D.S., PhD, assoc. prof.
Vilija Janulyte* – student
Margarita Musteikyte* – student
Ruta Bendinskaite* – D.D.S., PhD
Address correspondence to Dr. Alina Puriene, Institute of Odontology,
Zalgirio 115, Vilnius, Lithuania
E-mail: alina.puriene@mf.vu.lt
SUMMARY
The studies show a dental practitioner as a subject of a wide variety of physical and psychological
ailments. It is induced or aggravated by the work specificity and greatly affects the health of
dental professionals. Therefore, general health of dentists, especially effect of dental activity on it, is
present-day, important and as a matter of fact not well documented subject.
The aim of our review is to summarize and ascertain dental practice-related disorders influencing
the physical and psychological health of practitioner. Also we would like to highlight the most
vulnerable systems of the dental professional and to survey the best methods to overcome these
ailments.
Results. There is growing body of evidence that suggests surprisingly high vulnerability within
the dental profession to certain disorders and afflictions that can be categorized as practice-related.
Conclusions. In different countries dentists reported having poor general health and suffer from
various health-related problems. To enjoy and be satisfied with their professional and personal lives,
dentists must be aware of the importance to maintain good physical and mental health.
Key words: dentist's general health, physical disorders, psychological disorders.
INTRODUCTION
Dentists always knew the dentistry is not an
easy job. However until recently not many would
classify their profession as hazardous. This job is a
social interaction between helper and recipient in
their limited job setting and with personal characteristics.
A healthy dentist is one of the most important
components in a successful dental practice.
Despite the fact, that even 88 percent of dentists
report good or excellent health [47], some studies
show one out of ten dentists reports having poor
general health, and three out of ten dentists report
having poor physical state [29]. Many were feeling
unhealthy, worse than other high-risk-groups in a
human service working situation [39]. Dentists can
and do experience illnesses and problems that can
disrupt or impair a practice. Yet there is a growing
body of evidence that suggests increased vulnerability
within the profession to certain disorders and
afflictions that can only be categorized as practice
related. It is especially seen after we have gained
our independence. The work character and amount
of health care workers and dentists has changed a
lot.
The dentist is a subject to a wide variety of
physical and psychological ailments that are induced
or aggravated by the work environment and
they greatly affect the health of dental professionals.
PHYSICAL DISORDERS
When talking about physical disorders we have
to take into account musculoskeletal problems, dermatoses,
allergies and possible cross-infection.
The prevalence of musculoskeletal complaints
among dentists like among other health care workers
is high and well documented [2,20,39,73,
76,89,94]. Most of dentists (87.2 percent) reported
at least one symptom of musculoskeletal diseases
in the past 12 months [51]. A big study in Greece
showed: 62 percent of dentists reported at least
one musculoskeletal complaint, 30 percent chronic
complaints, 16 percent spells of absence and 32


Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1 1 1
percent ought medical care. Self-reported factors
of physical load were associated with the occurrence
of back pain, shoulder pain and, hand/wrist
pain. Physical load showed a trend with the number
of musculoskeletal complaints. The physical
load among dentists seems to put them at risk for
the occurrence of musculoskeletal disorders [2].
The dentistry seems to generate relatively high
muscular load on both trapezius and dominant extensor-
carpi-radialis muscle [59]. We have to account
not only instantaneous physical loads. They
cumulate (cumulative loads) and affect physical
health. Smaller loads cannot be ignored due to their
magnitude if their duration is long because the time
dependent properties of the tissues become modulating
factor. Thus the measurement of instantaneous
loads on tasks in dentists is not indicative of
the amount of cumulative stress experienced by
them [65].
Low-back pain is the most prevalent musculoskeletal
complaint [2,62,71,90]: in a Greek study –
46 percent prevalence [85], in an Australian study –
as much as 53.7 percent [51]. More than 25 percent
of all subjects with back pain reported the severe
chronic back pain [2]. Dentists who work in
the sitting position have more severe low back pain
than do those who alternate between sitting and
standing [71].
Prevalence of hand/wrist complaints among dentists
and especially dental hygienists is really high
[2,33,48,49,53,90]. Hand/wrist complaints follow low
back disorders [2,53] and result in a significant
higher chronicity than any other complaint [2]. The
prevalence of particularly carpal tunnel syndrome
among dentists is not very high, about 5 percent [33].
Though 56 percent of dental hygienists exhibit probable
or classic symptoms of carpal tunnel syndrome
[49].
Neck and shoulder complaints were less prevalent
than back pain. Musculoskeletal co morbidity
was high – 62 percent of all subjects reported at
least one musculoskeletal complaint, 35 percent reported
at least two musculoskeletal complaints, 15
percent reported at least three musculoskeletal complaints
and 6 percent reported spells of all four complaints
in the past 12 months [2].
Subjects with back pain more often reported neck
pain and hand/wrist pain than those without back
pain. Neck and hand/wrist pain was strongly associated
since 50 percent of subjects with neck pain
also experienced hand/wrist pain in the past 12
months. Age and gender were significant only for
neck pain. Senior people and women suffered from
neck pain more [2,76].
Educational level and working without breaks
were significant factors for shoulder pain. Living
alone was significant for neck and shoulder pain.
All complaints chronicity increased with age. Female
gender was significantly related to chronic back
and shoulder pain. Co morbidity was elevated among
those reported with higher physical load, lower job
control and working long hours [2].
Chronic musculoskeletal pain appears early in
dental careers, and more than 70 percent of dental
students of both sexes reporting pain by their third
year [76]. A study in Turkey gives us amazingly high
pain prevalence among dental students: headaches
(34 percent, 22 percent), neck pain (67 percent, 43
percent), back pain (56 percent, 47 percent), upper
limp pain (46 percent, 43 percent) and shoulder pain
(78 percent, 58 percent), respectively [91].
One cause of musculoskeletal disorders may be
mechanical vibrations affecting the organism through
the upper limbs and causing changes in the vascular,
neural and osteoarticular systems. These
changes may produce an occupational disease called
vibration syndrome. But on the basis of the available
literature it can not be decided unequivocally if
it exists a direct link between vibrations emitted by
the working dental instruments and the incidence of
symptoms characteristic of the vibration syndrome
[89].
Apart from vibrations, other harmful factors
connected with the profession seem to play a role,
and they modify the hand-arm symptoms [89].
The causes of musculoskeletal pain and disorders
common to dental operators are multifactorial.
There is relationship between the biomechanics
of seated working postures, repeated unidirectional
twisting of the trunk, working in one position
for prolonged periods, operator's flexibility and core
strength, operators knowing how to properly adjust
ergonomic equipment and physiological damage
or pain [94,95]. Studies indicate that strategies
to prevent the multifactorial problem of dental
operators developing musculoskeletal disorders
exist. These strategies address deficiencies in operator
position, posture, flexibility, strength and ergonomics
[94,95].
A study in Poland [90] showed that dentists
work in conditions which generally produce disorders
of the musculoskeletal system. The long working
time in the course of a day is used irrationally
from the point of view of ergonomics, and over the
years consequently increases the number of disorders
of the musculoskeletal system [90].
The relationship between physical and psychological
factors in dental profession was found: den-
A. Puriene et al. REVIEW


Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1 1 1
percent ought medical care. Self-reported factors
of physical load were associated with the occurrence
of back pain, shoulder pain and, hand/wrist
pain. Physical load showed a trend with the number
of musculoskeletal complaints. The physical
load among dentists seems to put them at risk for
the occurrence of musculoskeletal disorders [2].
The dentistry seems to generate relatively high
muscular load on both trapezius and dominant extensor-
carpi-radialis muscle [59]. We have to account
not only instantaneous physical loads. They
cumulate (cumulative loads) and affect physical
health. Smaller loads cannot be ignored due to their
magnitude if their duration is long because the time
dependent properties of the tissues become modulating
factor. Thus the measurement of instantaneous
loads on tasks in dentists is not indicative of
the amount of cumulative stress experienced by
them [65].
Low-back pain is the most prevalent musculoskeletal
complaint [2,62,71,90]: in a Greek study –
46 percent prevalence [85], in an Australian study –
as much as 53.7 percent [51]. More than 25 percent
of all subjects with back pain reported the severe
chronic back pain [2]. Dentists who work in
the sitting position have more severe low back pain
than do those who alternate between sitting and
standing [71].
Prevalence of hand/wrist complaints among dentists
and especially dental hygienists is really high
[2,33,48,49,53,90]. Hand/wrist complaints follow low
back disorders [2,53] and result in a significant
higher chronicity than any other complaint [2]. The
prevalence of particularly carpal tunnel syndrome
among dentists is not very high, about 5 percent [33].
Though 56 percent of dental hygienists exhibit probable
or classic symptoms of carpal tunnel syndrome
[49].
Neck and shoulder complaints were less prevalent
than back pain. Musculoskeletal co morbidity
was high – 62 percent of all subjects reported at
least one musculoskeletal complaint, 35 percent reported
at least two musculoskeletal complaints, 15
percent reported at least three musculoskeletal complaints
and 6 percent reported spells of all four complaints
in the past 12 months [2].
Subjects with back pain more often reported neck
pain and hand/wrist pain than those without back
pain. Neck and hand/wrist pain was strongly associated
since 50 percent of subjects with neck pain
also experienced hand/wrist pain in the past 12
months. Age and gender were significant only for
neck pain. Senior people and women suffered from
neck pain more [2,76].
Educational level and working without breaks
were significant factors for shoulder pain. Living
alone was significant for neck and shoulder pain.
All complaints chronicity increased with age. Female
gender was significantly related to chronic back
and shoulder pain. Co morbidity was elevated among
those reported with higher physical load, lower job
control and working long hours [2].
Chronic musculoskeletal pain appears early in
dental careers, and more than 70 percent of dental
students of both sexes reporting pain by their third
year [76]. A study in Turkey gives us amazingly high
pain prevalence among dental students: headaches
(34 percent, 22 percent), neck pain (67 percent, 43
percent), back pain (56 percent, 47 percent), upper
limp pain (46 percent, 43 percent) and shoulder pain
(78 percent, 58 percent), respectively [91].
One cause of musculoskeletal disorders may be
mechanical vibrations affecting the organism through
the upper limbs and causing changes in the vascular,
neural and osteoarticular systems. These
changes may produce an occupational disease called
vibration syndrome. But on the basis of the available
literature it can not be decided unequivocally if
it exists a direct link between vibrations emitted by
the working dental instruments and the incidence of
symptoms characteristic of the vibration syndrome
[89].
Apart from vibrations, other harmful factors
connected with the profession seem to play a role,
and they modify the hand-arm symptoms [89].
The causes of musculoskeletal pain and disorders
common to dental operators are multifactorial.
There is relationship between the biomechanics
of seated working postures, repeated unidirectional
twisting of the trunk, working in one position
for prolonged periods, operator's flexibility and core
strength, operators knowing how to properly adjust
ergonomic equipment and physiological damage
or pain [94,95]. Studies indicate that strategies
to prevent the multifactorial problem of dental
operators developing musculoskeletal disorders
exist. These strategies address deficiencies in operator
position, posture, flexibility, strength and ergonomics
[94,95].
A study in Poland [90] showed that dentists
work in conditions which generally produce disorders
of the musculoskeletal system. The long working
time in the course of a day is used irrationally
from the point of view of ergonomics, and over the
years consequently increases the number of disorders
of the musculoskeletal system [90].
The relationship between physical and psychological
factors in dental profession was found: den-
A. Puriene et al. REVIEW

Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1 1 3
There are few evidences of higher hepatitis infection
risk in dental practice. The most hazardous
infection for medical staff is hepatitis B. It is most
frequently acquired through micro trauma. Even 10-
39 percent of medical staff and 12-27 percent of
dental team staff revealed seropositivity of hepatitis
B virus [47]. Greater number of years of occupation
in dentistry was independently and significantly
(P = .0004) associated with seropositivity to
hepatitis A virus. The calculated odds ratio showed
that each year of work increased the likelihood of
being seropositive by 1.06 (6 percent). Subjects
tended to have higher seropositive rates if they were
older, had a greater number of children, had a
greater number of siblings, had worked in hospitals
and worked with children (pediatric dentists and
orthodontists) [3].
A source of hepatitis and many other infectious
hazards could be a percutaneus injury. Out
of the dentists interviewed, 31.1 percent reported
accidents, with a mean incidence of 2.02 accidents
each professional year [63]. When dental personnel
were analyzed, dentists experience it most often:
36 percent of percutaneus injuries were reported
by dentists, 34 percent by oral surgeons, 22
percent by dental assistants, and 4 percent each
by hygienists and students. Almost 25 percent involved
anesthetic syringe needles. Out of 87 needle
stick injuries, 53 percent occurred after needle use
and during activities in which a safety feature could
have been activated (such as during passing and
handling) or a safer work practice used [15]. It
was found, that 90 percent of dentists recapped
needles after using them, while only 8.1 percent
re-used gloves [8].
Dentists knowledge regarding infectious diseases
that can be acquired or transmitted in the dental surgery
and the vaccinations recommended are quite
poor: only 44.1 and 32.4 percent correctly indicated
all infections that can be acquired or transmitted during
their activity. Only half of the dentists knew that
they should be vaccinated against hepatitis B and
influenza. A large proportion (85.7 percent) reported
receiving the hepatitis B vaccine, but only 56.2 percent
the three doses. [17].
One study assessed attitudes toward occupational
health and knowledge of the area: clinicians
rated occupational health to be less important than
did interns and students. Prior work experience did
not affect performance; however, students from
"blue collar" families scored higher in both knowledge
and attitudes than those from "white collar"
families. Women scored higher in both areas than
did men. There was no correlation between number
A. Puriene et al. REVIEW
of hours of occupational medicine in school and performance,
either overall or within each level. This
study suggests that enthusiasm for occupational
health declines with training, and that knowledge
gains are erratic [86].
Regardless of gender, dentists do experience
other problems that may disrupt or impair dental
practice, including substance abuse involving alcohol
and/or other drugs. Therefore, dentists need
to understand gender differences associated with
risk for abuse of alcohol and other substances; related
physical, emotional, and professional effects;
and other aspects of professional health and
wellness [74].
PSYCHOLOGICAL DISORDERS
Not only physical impairments affects dentist's
health. Job-related psychological disorders also contribute
greatly. Factors that affect dentist's psychological
status can be job-related stress, tension, depression,
emotional exhaustion, depersonalization.
Dental practice is stressful. Dentists have to
deal with many significant stressors in their personal
and professional lives [30]. There is some evidence
to suggest that dentists suffer a high level of jobrelated
stress [7,22,23,62,73].
83 percent of dentists' perceived dentistry as
being "very stressful" [7], nearly 60 percent perceived
dentistry as more stressful than other professions
[60]. Dentists indicated running behind
schedule, causing pain, and heavy work load, late
and anxious patients as well being the most intense
stressors in their work [60, 99]. Dentists, who reported
that dental anxiety was primarily the result
of general psychological problems in patients, usually
had solo practices older than 18 years and reported
high perceived stress [60]. Clinicians experience
numerous workplaces, financial, practice
management and societal issues for which they often
are unprepared after finishing a university.
The difference in reported levels of stress between
dental specialties was not found. Practitioners
working in the field of pediatric dentistry reported
the highest median levels of stress though
this trend was not significant [67].
A large number of factors are implicated in
stress situations, including low autonomy, work overload,
and lack of congruence between power and
responsibility. Doctors and dentists who take on a
teaching role in addition to their clinical role may
increase their levels of stress, but there is also evidence
that this dual role may reduce job-related
stress [82].


1 4 Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1
Stress may produce "burnout". It is a syndrome
of emotional exhaustion, depersonalization and reduced
personal accomplishment, a particular type
of job-related stress reaction. It is a response to the
chronic emotional strain of dealing extensively with
other human beings, particularly when they are
troubled or having problems. The values of burnout
and it's constituents among dental workers are amazingly
high [7,11,22,23,28,68,93]. Recent findings suggest
that burnout has features of maladaptive coping
in the short term but is, paradoxically, protective
in the longer term. Dentists are prone to burnout
due to the nature of their work but may be able to
prevent it if they can recognize the burnout process
and take regular holiday breaks.
Burnout is assumed to have an adverse influence
on patient care, although no dental studies, as
yet, have tackled the issue [22].
The study in England exhibited high overall burnout
in 10.6 percent of examined dentists. Emotional
exhaustion was found in 25.53 percent, depersonalization
– 8.88 percent and reduced personal accomplishment
in 34.42 percent of dentists [68]. When the
Spanish dentists were questioned, high values were
detected in emotional exhaustion – 54.3 percent,
depersonalization – 55.6 percent; personal achievements
– 6.9 percent [93]. Gender differences in burnout
among dentists do exist. Male dentists reported a
higher score of depersonalization than did female
dentists [11,23]. However, results indicate that underlying
factors, such as working hours, have a profound
effect on these differences [11]. Men work
more hours and work part time less frequently [96].
Dentists are not unique experiencing high overall
burnout. Very similar data is presented among all
primary care practitioners: 19% of respondents had
a high score for emotional exhaustion, 22% had a
high score for depersonalization or cynicism and 16%
had a low score for professional accomplishment,
32% had a moderate degree and 4% had high degree
of burnout [23]. A high degree of burnout is
associated with the male sex, practicing in a rural
area, and excessive perceived stress due to global
workload, patient's expectations, and difficulties to
balance professional and private life, economic constraints
in relation to the practice, medical care uncertainty
and difficult relations with non-medical staff
at the practice [23].
Burnout comes about in situations where there
is a focus on problems, lack of positive feedback,
the level of emotional stress is high and where problems
are chronic [68].
Depression may be a consequence of prolonged
experience of burnout [41].
Recent findings suggest that burnout has features
of maladaptive coping in the short term but is,
paradoxically, protective in the longer term [41].
There is a relationship between emotional load
and volume of patients treated. Depersonalization
levels decrease with age and it could be due to a
number of factors – socialization skills increasing
with age, a slowing of pace of work which allows
more personal contact, or the establishment of personal
relationships with patients over time [68]. Older
dentists work fewer hours, with a larger impact of
age seen among men [96]. Emotional support may
be gained from co-workers that are why the numbers
of burnout syndrome may decrease in the larger
practice groups. Conversely, a particular characteristic
of private practice is the high level of control.
It allows dentists to have control over their working
conditions: a factor which is reported to help reduce
stress levels. It is also related to income, autonomy
and the match between technical aspirations
and practical outcomes [68].
Higher levels of depersonalization in unmarried
dentists compared with those who were married suggests
that involvement with a spouse and children
makes married people more experienced in dealing
with personal problems [68].
The higher levels of personal accomplishment
were in dentists with post-graduate qualifications
[68].
Also specialists, were more satisfied with their
psychosocial work environment than general practitioners,
especially regarding their personal control
over their work and the stimulation of their work.
The specialists also had more self-confidence and
experienced less anxiety than general practitioners
and head dentists [68,81].
Lack of career perspective appears to be the
stress factor strongly related to burnout [24]. This
relation should stimulate serious attention for career
planning among dentists.
The conceptual basis of burnout would seem to
imply that physical environment is probably of minor
importance in the process and no actual work
place condition could be demonstrated to be correlated
with high burnout levels, it would be prudent
to make the practice environment as pleasant as
possible. For, apart from directly reducing stress on
the dentist, it might reduce the anxiety level of patients,
and thus the emotional load on the dentist
[24,68].
There tend to be some differences in burnout
scores relating to the levels of professional isolation.
The lack of hierarchal structure to general
dental practice means that dentists have constantly
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Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1 1 5
to rely on their own emotional resources in the
clinical situation. This contrasts with the worker
within an organization where there are colleagues
with whom to share the emotional strain of contacts
with distressed clients. Furthermore, superiors
in a hierarchy are available for support and
help when necessary, which can substantially alleviate
anxiety. This argument is counterbalanced
by the issues of autonomy and control. Large organizations
are able to deal with issues such as
staff discipline, communication with other organizations
and financial control. In small organizations
such as general dental practice, the stress
associated with these activities is concentrated to
a small number of people, frequently the dentist
[28,62,68]. A very interesting study identified the
specific situations that most frequently produce
stress. The majority of these situations could be
classified as being related either to dental procedures
and office organization or to interpersonal
relationships involving patients and/or office personnel
[10]. So, dentists consider clinical matters
their greatest stress [10,40].
Differences of individual responses to stress
may be attributable to personality factors and differences
in coping styles, and tend to support the
hypothesis that stress is a unique, perceptual and
experimental phenomenon [13]. The older dentists
are less stressed than their younger counterparts.
Some issues like those concerned with finance and
patient-management, appear to affect both groups
more or less equally, which suggests that these issues
are of global, rather than specific concern. From
a theoretical point of view, the findings tend to contradict
the generally – held belief that getting older
is automatically accompanied by degeneration and
problems of adaptation to life changes. On the contrary,
seemingly favorable adaptation and low levels
of stress are evident in most of the older dentists
[14,60].
Nervous psychological state, tension, depression
and others signs of psychological impairment also
has to be taken into account when talking about jobrelated
stress in dental practice. A huge study in
England shows amazing results: sixty percent of general
dental practitioners feel nervous, tense or depressed,
58.3 percent reported headache, 60 percent
reported difficulty in sleeping at night and 48.2
percent reported feeling tired for no apparent reason.
Levels of minor psychiatric symptoms were
high, with 32.0 percent of cases identified [62]. The
other study found that gender was associated with
depression in two specialties: periodontics and pediatric
dentistry [55].
The important thing is that only 15 percent of
depressed dentists receive treatment [55].
Job-related stress and all psychological impairments
it has led to affects dentists personal as well
as dental family life. The effect of the dentist's office-
related stress is directly felt in the family, especially
by the spouse. Strong coping patterns result
when dentists and spouses maintain a balance
of time and responsibility, satisfaction in work and
family activity, regular communication, sharing of
decision making, good physical health, and the inclusion
of an active exercise program within multiple
demands on their time [64].
A study of Sweden general practice dentists revealed
that females constitute one-quarter of all dentists.
These female dentists suffer from many problems
relating to their psychosocial working conditions.
There are wide discrepancies between their
perception of the ideal job situation and reality [38].
Physicians, who report high levels of work
stress, also report lower levels of marital satisfaction
and a higher prevalence of psychiatric symptoms
[52].
Dentists are much like physicians in their reports
of overall work stress, and the similarities and
differences regarding specific stressors suggest
these professions are very alike in reporting the
stresses of professional practice. [52].
Taking into account dental students, it must be
assumed that the level of emotional exhaustion was
higher in dental students than medical students; and,
second, that general psychological distress and
course related stress levels were associated with
the nature of the course and the immediate living
conditions of the students [42].
In our day remuneration system has led dentists
to long working hours, leaving little time to relax
from work, participate in family life [56,61]. A
huge study in Canada showed that more than 10
percent of dentists see equally or more than 30 patients
per day [56]. These factors may all be considered
to be part of current general dental practice
and they really affect dentist's health.
It is very interesting that particular traits are common
among those who decide to pursue careers in
dentistry. And these traits make dentists prone to professional
burnout, anxiety disorders and clinical depression
[21]. And that differences in approach to
work and perceived workplace climate mainly reflects
stable, long-term individual differences in doctors
themselves, reflects in measures of personality and
learning style [58]. In many cases the psychological
variables (distress, emotional exhaustion or intensity
of stressors) were influenced by gender [25,42].
A. Puriene et al. REVIEW

1 6 Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1
Although dentists suffer from psychical impairments,
they do not seem to be using alcohol,
tobacco and other potentially addicting drugs in
numbers greater than the nonprofessional population
[6,46,84]. But alcohol use is related to stress
among dental professionals [62]. The media repeatedly
portrays dentists and other health professionals
as being at risk of committing suicide
[1,83,87]. While this message often is accepted
without question, there are little reliable data available
that verifies this alleged risk. There is little
valid evidence that dentists are more prone to
suicide than the general population, although some
related data suggest that female dentists may be
more vulnerable [4,34,35,78,83]. It is very interesting
that male doctors seem to be at less risk than
men in the general population. The excess risk of
suicide in female doctors highlights the need to
tackle stress and mental health problems in doctors
more effectively [1,34].
On the contrary, the other study [36] revealed
that the physicians as a whole still had a higher suicide
rate than other university graduates and the general
population, both among men and women compared
to 23.5 per 100.000 person-years and 8.0 per
100.000 person-years among male and female no
graduates, respectively. The suicide rate among female
physicians was twice as high as that of the
general population as well as other female graduates,
even in the 1990s. Of interest, suicide rates
increased steeply by age among physicians and other
graduates, whereas for no graduates, the rate was
highest among those ages 40-60 years [36].
Also analysis of death distribution according to
underlying causes indicated the absence of significant
differences that might suggest increased risk
of death for dentists. Dentists' deaths did not present
worse indications for global and specific categories
of infectious diseases, central nervous system or circulatory
diseases [4]. There is only a slight tendency
of a favorable risk pattern for lung cancer
and overall cancer occurrence [85]. All these observations
suggest that dentistry can be considered
a safe profession, at least regarding exposure to
systematic risk of death. It may be because of dentists
report immediate results and aesthetics, and
long-term results of working with patients to be the
most rewarding aspects. All job resources showed
a positive correlation with job satisfaction [27].
Slightly less than half of the dentists were satisfied
with their profession and the personality types over
represented in dentistry tended to have a higher level
of satisfaction and a lower level of burnout compared
to their cohort group [7,9].
The philosophy inherent in the remuneration system
raises issues of quantity and quality. The combination
of a fee per item system of payment combined
with a fixed pool of available money witch is
not forecast to increase has strong implications related
to burnout, poorer mental health, stress
[6,9,68,80,98]. Short term increases in profit for individuals
can be achieved by higher work output,
but in the longer term as the system adjusts the increases
are eroded, though the increase work load
and therefore stress levels have been sustained. This
also has implications for quality, where quality is
poorly defined, if at all and only rewarded negatively
with retrospective punitive action. Practitioners who
feel unfairly penalized may have a greater tendency
to burnout. Furthermore, in systems of low profitability,
the ability of dentists to reinvest in their practices
and thereby improve the working environment,
increase their patients confidence and decrease their
anxiety levels is limited [68].
A study in Sweden describes how the female
general practice dentists think of the dimensions that
the dentistry profession should contain. It concluded
that the gulf between ideal and reality is wide, especially
concerning the dentist's influence on important
decisions. There must be good communication
and democracy at work, and based on freedom and
the employees influence, could bring ideal and reality
closer [37].
In addition to the vulnerabilities of the human
condition – addictive disorders, psychiatric illnesses,
family and relationship problems, or the many varieties
of human misery – dentists have undergone a
powerful process of socialization into their professional
role that makes it difficult to seek help for
themselves. Stigma about addictive and psychiatric
illnesses continues to be a problem despite significant
advances in scientific understanding of these
disorders. Many people, especially those in positions
of community visibility as dentists are, still struggle
with shame when they associate problems with personal
failure [50]. One may find out, that the reasons
for leaving practice included financial problems,
stress, and external regulation concerns. Current
careers varied widely, with business, teaching, medicine,
and investing being the most common. Respondents
ranked their current careers as considerably
more favorable on measures of perceived creativity,
freedom, belonging, and whether they would
choose the same career again. These findings indicate
that there was a difference between the perception
of a dental career and the reality of clinical
practice for the study sample. Reasons to leave
dental practice are not health problems [75].
REVIEW A. Puriene et al.


Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1 1 7
There is a need to acknowledge the existence
of the problems within the dental profession and to
establish ways to prevent and alleviate stress and
other psychological disorders among dental practitioners
[16,30]. Higher patient expectations, higher
targets for provision of dental care will put increased
demands upon dentists [45]. The highest
ranked individual stressor: 61.9 percent, was 'running
behind schedule'. [98]. Discussion of the problem
could take place at appropriate points in the
professional training program and throughout the
career of a dentist. This may, in itself, be helpful
by allowing individuals to realize that their feelings
are not unique nor representing a personality defect.
Davidove maintains that healthy self-criticism
can help bolster the dentist's sense of self-esteem
and can work as a prophylaxis against depression
[16,45]. Researches offers supervision and support
groups as a simple and powerful mean to
ease the burdens of medical practice and prevent
disillusionment and subsequent impairment among
health care workers [18,66,68]. Occupational medicine
clinics also serve as occupational training and
consultative site [79]. Dental societies, family and
friends are also in an ideal position to provide resources
and support. Active membership in local,
state and national organizations can lessen the feelings
of professional isolation and can provide contacts,
which can help starting practitioners improve
their practice environments [97]. Even the Stress
Thermometer (an easily accessible Internet-based
instrument for feedback on work stress and burnout)
was made-up to effectively call attention to
sensitive personal issues concerning work-related
stress and burnout [12]. Furthermore, the risk of
female suicides requires particular monitoring in
the light of the very large increase in the numbers
of women entering medicine [34]. All these measures
should be strongly promoted and developed
to help to overcome all these dental society problems.
Emphasis on faculty training and clinical rotations
should be strongly placed also. With reservations,
it can be concluded that the prevention
program does have a positive effect on burnout
scores among dentists, while different forms of
self-initiated prevention activities also appeared to
be effective [26].
In order to improve dental staff work in the
USA, The White Coat Ceremony was established.
Many dental schools use to mark the transition to
patient care. It is an opportunity to reflect on the
values of dental practice. Eight principles are offered
for consideration: 1) patient care is the point
of practice; 2) the doctor-patient relationship is
essential; 3) discuss options and possibilities; 4)
mistakes will be made; 5) tell the truth; be assertive;
7) consult; and 8) manage your stress and
your life. It may also be a good point in preventing
dental staff from stress and problems in their lives
[69].
As mentioned above studies indicated the occupational
health knowledge gained from school is
erratic. The curriculum reform should be developed.
The practitioner is recommended to be actively concerned
about problems. Numbers of percutaneus injury
show that dental practices should have a comprehensive
written program for preventing needle
stick injuries that describes procedures for identifying,
screening and, when appropriate, adopting
safety devices; mechanisms for reporting and providing
medical follow-up for percutaneous injuries;
and a system for training staff members safe work
practices and the proper use of safety devices [15].
In order to avoid part of musculoskeletal disorders
among dentists altering position between sitting and
standing is recommended [71]. A thorough understanding
and controlling of the underlying physiological
mechanisms leading to them is necessary to develop
and implement a comprehensive approach to
minimize the risks of a work-related injury. Dentists
must be highly aware of the importance of maintaining
good physical and mental health to enjoy and
be satisfied with their professional and personal
lives.
CONCLUSIONS
In different countries dentists reported having
poor general health and suffer from various healthrelated
problems. The dentistry has always been
known as uneasy occupation therefore one must take
into account serious difficulties before attending
medical school. First of all, students must be aware
of the health risks in dentist's job. Talking about musculoskeletal
disorders it might be assumed that
knowledge in ergonomics may be of some use. Secondly,
all sorts of protection must be used during
treatment in order to prevent infectious diseases and
other injuries. Furthermore, dentists must be taught
about coping with stress patterns. There are some
points in preventing psychological discrepancies. To
enjoy and be satisfied with their professional and
personal lives, dentists must be aware of the importance
to maintain good physical and mental health.
It is important to enjoy their lives, exercise physically,
have a hobby, create a harmonious family,
communicate with colleagues and keep learning all
their lives.
A. Puriene et al. REVIEW

1 8 Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 1
REVIEW A. Puriene et al.
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Received: 15 02 2007
Accepted for publishing: 27 03 2007
REVIEW A. Puriene et al.



The relationship between blood serum lipids and periodontal condition

96 Stomatologija, Baltic Dental and Maxillofacial Journal, 2006, Vol. 8., No. 3.
The relationship between blood serum lipids and
periodontal condition
Giedre Valentaviciene, Pajauta Paipaliene, Irena Nedzelskiene, Juozas Zilinskas, Ona Vidute
Anuseviciene
Giedre Valentaviciene – D.D.S., ass. prof., Department of Dental and
Oral Diseases, Kaunas Medical University, Lithuania
Pajauta Paipaliene – D.D.S., Ph D, Assoc. Prof., Department of
Dental and Oral Diseases, Kaunas Medical University,
Lithuania
Irena Nedzelskiene – engineer programmer at the Department of
Dental and Oral Diseases, Kaunas Medical University,
Lithuania
Juozas Zilinskas – D.D.S., private practice
Ona Vidute Anuseviciene – assist. Institute of Anatomy, Kaunas Medical
University, Lithuania
Address correspondence to Dr. G. Valentaviciene, Eivieniu 2, Dep. of
Dental and Oral Diseases, Kaunas Medical University, Lithuania
SUMMARY
The aim of the study: the study analyzed he relationship between blood serum lipids and
periodontal condition, as well as the relationship between the left ventricular mass index and the
condition of periodontium. The study included 261 subjects – 140 women and 121 men. Mean age
of the subjects was 38 years. The condition of periodontal tissues during the study was evaluated
with the help of the CPITN index (Community Periodontal Index of Treatment Needs). The study
was performed at Kaunas University of Medicine (KMU) Clinic of Dental and Oral Diseases.
Laboratory blood lipid studies were performed at the laboratory of the Hospital of Kaunas University
of Medicine (HKUM). The studies included the determination of the total blood cholesterol
level, triglyceride level, HDL cholesterol level, and LDL cholesterol level (mmol/l). Patients with
hypertension (102 patients) underwent ultrasound examination of the heart at KMU Clinic of
Cardiology. On the basis of the findings of the ultrasound study, left ventricular mass index (g/m2)
was calculated.
The findings of our study showed that there was no difference in the blood serum concentration
of total cholesterol, triglycerides, HDL cholesterol, and LDL cholesterol between people with
healthy periodontium and those with gingivitis or periodontitis. Mean rank of the left ventricular
mass index in subjects with healthy periodontium or gingivitis (CPITN codes 0, 1, 2) was 48.3, and
in subjects with periodontitis (CPITN codes 3, 4) – 61.36 (p<0.05).
Key words: periodontal diseases, cardiovascular diseases, cholesterol, left ventricular mass.
INTRODUCTION
Although a number of studies have been performed
recently on the possible association between cardiovascular
diseases (CVDs) and periodontium, this association
is not thoroughly understood yet [1,2,3,4].
CVDs are common all over the world, and atherosclerosis
of coronary arteries is considered to be the leading
cause of premature death among men [5]. The pathological
background of the atherosclerosis of coronary arteries is
the formation of atherosclerotic plaque, which additionally
induces other cardiovascular diseases [6].
The main risk factors for CVDs are age, male sex, hypercholesterolemia
(especially in case of cholesterol with
low density lipoproteins (LDL)), smoking, systemic hypertension,
and diabetes mellitus [7]. The majority of risk factors
of CVDs are also considered to be risk factors for
periodontal diseases (periodontitis) [8]. The role of inflammation
in the development of atherosclerosis has been
studied as well [9]. Studies found that atherosclerosis may
be caused by several viral (cytomegalo virus and herpes
virus and bacterial (Chlamydia pneumoniae, Helicobacter
pylori) pathogens [10, 11].
A hypothetical relationship between damage to periodontium
and atherosclerosis could be explained by the
effect of a chronic inflammatory process on blood rheology,
and a direct effect of active cytokines and activated
lymphocytes and monocytes on the tissues of blood vessel
walls [12,13]. Periodontitis is a chronic inflammatory
disease that is characterized by a Th1 reaction and the
release of cytokines (such as TNF-a and IL-b) [14,15]. It
was determined that these cytokines also influence the
development and progression of atherosclerosis [16,17].
Hypertension is also a very important risk factor for
CVDs. Despite high prevalence of hypertension (as well
as its immense prognostic value), there are few findings
on the association between elevated blood pressure and
the condition of the periodontium [18].
It was found that 1/3 of patients with hypertension
have an abnormal increase in the left ventricular mass. It
is known that left ventricular (LV) hypertrophy is associated
with an increased risk for various CVD complications
irrespectively of blood pressure and other factors
[19].
The aim of the study: this study analyzed the relationship
between blood serum lipids (as a well known CVD
factor) and the condition of the periodontium, as well as
the relationship between left ventricular mass index and
the condition of the periodontium.
SCIENTIFIC ARTICLES
Stomatologija, Baltic Dental and Maxillofacial Journal, 8:96-100, 2005


Stomatologija, Baltic Dental and Maxillofacial Journal, 2006, Vol. 8., No. 3. 97
Fig. 2. The relationship of the CPITN index with trigliceride
Fig. 3. The relationship of the CPITN index with HDL
Fig. 1. The relationship of the CPITN index with total cholesterol
Fig. 4. The relationship of the CPITN index with LDL
MATERIAL AND METHODS
The study included 261 people – 140 women and 121
men. Mean age of the subjects was 38 years. The examination
of the oral cavity was performed at KMU Clinic of Dental
and Oral Diseases, laboratory blood lipid tests were performed
at HKUM laboratory, and measurements of the subjects’
arterial blood pressure, as well as cardiac ultrasound
studies, were performed at KMU Clinic of Cardiology.
The condition of periodontal tissues was evaluated
with the use of the CPITN (Community Periodontal Index
of Treatment Needs) index [20]. The determination of this
index was performed with the help of a stomatological mirror
and a periodontal probe. The determination of the
CPITN index was performed the following way: teeth in the
lower and upper jaws were divided into sextants. One teeth
of each sextant was examined (16, 11, 26, 36, 31, and 46).
The following codes were used in the evaluation:
Code 0 – healthy periodontal tissues;
Code 1 – bleeding after probing;
Code 2 – supragingival and subgingival calculus;
Code 3 – 4-5 mm deep pathological pockets;
Code 4 – 6 mm and deeper pathological pockets.
The findings of the study were recorded in a table;
the biggest code for the examined tooth was recorded:
16 11 26
46 31 36
During tests at the HKUM laboratory, total blood cholesterol
levels, as well as the blood levels of triglycerides,
high-density cholesterol (HDL) and low-density choles-
G. Valentaviciene et al. SCIENTIFIC ARTICLES



Stomatologija, Baltic Dental and Maxillofacial Journal, 2006, Vol. 8., No. 3. 99
(statistical Package for Social Sciences) for document accumulation
and analysis. The interrelationship of attributes
was evaluated using c2 criterion, and the comparison of
mean values was performed suing Student’s t-criterion.
When evaluating quantitative findings that did not have
normal distribution, comparison tests for non-parametric
values were used. Differences with significance level below
0.05 were considered to be significant.
RESULTS AND DISCUSSION
The statistical analysis of the findings, and the evaluation
of the obtained results showed that in male subjects,
mean total blood cholesterol level was 5.77±0.09,
mean triglyceride level – 1.45±0.13, mean high density
cholesterol (HDL) level – 1.42±0.03, and mean low density
cholesterol (LDL) – 3.79+±0.08. The respective values
in female subjects were 5.83±0.32, 1.1±0.11, 1.52±0.02,
and 3.49±0.08.
The analysis of the relationship of blood serum lipids
with the CPITN index in men yielded the following results:
mean total blood cholesterol level at CPITN Code 0 (healthy
periodontal tissues) – 6.19±0.45, at code 1 (bleeding after
probing) – 5.26±0.2, at code 2 (supragingival and subgingival
calculus) – 5.74±0.13, and at codes 3, 4 (4-6 mm and
deeper periodontal pockets) – 5.86±0.14 (Fig. 1). The respective
values for mean blood triglyceride levels were
the following: CPITN Code 0 – 2.15±0.91, code 1 –
0.92±0.09, code 2 – 1.46±0.18, and codes 3, 4 – 1.27±0.11
(Fig. 2). Mean values for blood HDL levels were the following:
CPITN code 0 – 1.32 ±0.11, code 1 – 1.43±0.12,
code 2 – 1.45±0.04, and codes 3, 4 – 1.39±0.04 (Fig. 3).
Mean values for blood LDL levels were the following:
CPITN code 0 – 4.19±0.43, code 1 – 3.54±0.24, code 2 –
3.73±0.12, and codes 3, 4 – 3.88±0.13 (Fig. 4).
The analysis of the results in the group of female subjects
yielded the following findings:
Mean total blood cholesterol level at CPITN Code 0 –
5.72±0.33, at code 1 – 5.56±0.21, at code 2 – 5.93±0.454, and
at codes 3, 4 – 5.48±0.21 (Fig. 5). The respective values for
mean blood triglyceride levels were the following: CPITN
Code 0 – 0.87±0.1, code 1 – 0.95±0.11, code 2 – 1.17±0.16,
and codes 3, 4 – 0.94±0.07 (Fig. 6). Mean values for blood
HDL levels were the following: CPITN code 0 – 1.6 ±0.09,
code 1 – 1.58±0.19, code 2 – 1.55±0.03, and codes 3, 4 –
1.56±0.06 (Fig. 7). Mean values for blood LDL levels were
the following: CPITN code 0 – 3.84±0.28, code 1 – 3.53±0.3,
code 2 – 3.45±0.09, and codes 3, 4 – 3.49 ±0.22 (Fig. 8).
Literature contains various findings about possible
relationship between blood serum lipids and periodontal
condition. Katz, J. et al. [23] indicate that in men, total
blood cholesterol and LDL levels are significantly higher
in patients with periodontitis (CPITN codes 3, 4), compared
to patients with healthy periodontium and those with
gingivitis (CPITN codes 0, 1, 2). These authors do not
indicate significant findings in the groups of females. The
association between periodontal condition, lipid concentration,
and CVDs is indicated in other articles as well [24,
25]. Loesche, W. et al. [26] determined a significant association
between, periodontal conditions and the concentration
of triglycerides in blood.
Krause, S. et al. [27] states that hyperlipidemia causes
hyperactivity of white blood corpuscles. It was determined
that hyperactivity of white blood cells (e.g. increased production
of oxygen radicals) may be associated with the
development of periodontitis in adults [28].
Cutler, C. W. et al. [29] in their article stated that there
exists a close relationship between damage to the periodontium,
increased concentration of lipids in blood, and
the presence of Porphyromonas gingivalis antibodies. Although
the studied sample was small (26 people), this study
showed that higher triglyceride levels might modulate the
production of IL-Ib polymorphonuclear leucocytes stimulated
by P. gingivalis.
Morrison, H. I. et al. [30] in their article mention total
blood cholesterol level, c-reactive protein, and fibrinogen
as possible intermediate factors that associate periodontitis
with increased risk for CVDs.
However, these findings do not allow for the determination
of causality, i.e. whether periodontal diseases may
increase blood lipid concentration, or hyperlipidemia exists
as the same risk factor for periodontal diseases and
CVDs [23].
Our study did not show any significant differences in
blood concentration of total cholesterol, triglycerides,
HDL, and LDL between people with healthy periodontium
and those with gingivitis or periodontitis (in both male
and female subjects). The results may have been influenced
by the young age of the subjects (38 years) as well
by the fact that this study did not analyze such aspects as
physical activity, nutrition, experienced stress, etc. Similar
findings were obtained in the study performed by Hujoel,
P. P. et al. [31].
Our study also determined the relationship of LV mass
index (in patients with hypertension) with the CPITN index.
The evaluation of the obtained findings showed that
mean LV mass index in subjects with healthy periodontium
or with gingivitis (CPITN codes 0, 1, 2) was 92.92±2.7, while
that in subjects with periodontitis (CPITN codes 3, 4) –
97.54±11.2. The comparison of these mean values did not
yield any significant results. However, the Kolmagorov-
Smirnov test showed an abnormal distribution, and the
non-parameter study method was applied (Mann-Whitney
test).
The results of the test were the following: mean rank
value of the LV mass index in subjects with healthy periodontium
of gingivitis was 48.3, while in subjects with periodontitis
– 61.36 (p<0.05). Similar results were obtained
by Angeli, F. et al. [32]. Possible mechanisms that associate
LV mass index and periodontal condition are not fully
understood. It is thought that in case of patients with hypertension,
both hypertrophied heart and periodontium
may be characterized by common microcirculatory dysfunction
and rarefaction of the network of arterioles and
capillaries.
Elevated pressure may play a role in the development
of LV hypertrophy and general narrowing of the lumen of
micro blood vessels. This may result in ischemia on the
levels of both the heart and the periodontium [33].
Thus, a simple evaluation of the periodontal condition
may be useful for the evaluation and specification of
CVDs when examining patients with hypertension.
G. Valentaviciene et al. SCIENTIFIC ARTICLES

100 Stomatologija, Baltic Dental and Maxillofacial Journal, 2006, Vol. 8., No. 3.
Received: 26 04 2005
Accepted for publishing: 25 09 2005
REFERENCES
1. Muller HP. [Does chronic periodontitis play a role in the pathogenesis
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2. Emingil G, Buduneli E, Aliyev M, Ahilli A, Atilla G. Association
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3. Genco R, Offenbacher S, Beck J. Periodontal disease and cardiovascular
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4. Howell TH, Ridker PM, Ajani UA, Hennekens CH, Christen WG.
Periodontal disease and risk of subsequent cardiovascular disease in
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5. Ross R. Atherosclerosis – an inflammatory disease. J Med 1999;
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Širdies ligos. – Kaunas; 2001, p. 5–7.
7. Lowl GDO. Etiopathogenesis of cardiovascular disease: Hemostasis,
thrombosis and vascular medicine. Ann Periodontol 1998, 3:
114–127.
8. Beck J, Offenbacher S, Williams R, Gibbs P, Garcia R. Periodontitis:
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10. Sorlie PD, Adam E, Melnick SL. Cytomegalovirus, herpesvirus and
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33–7.
11. Patel P, Carrington D, Strachan DP. Fibrinogen: a link between
chronic infection and coronary heart disease. Lancet 1994; 343:
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12. Danesh J, Collins R, Peto R. Chronic infection and coronary heart
disease: Is there a link? Lancet 1997; 350: 430–6.
13. Libby P, Egan D, Sharlatos G. Roles of infections agents in atherosclerosis
and restenoses. Circulation 1997; 96: 4095–103.
14. Dongari–Bagtzoglou Al, Ebersole JL. Increased presence of
interleukin – 6 (IL – 6) and IL – 8 secreting fibroblast subpopulations
in adult periodontitis. J Periodontol 1998; 69: 899 – 910.
15. Lo YJ, Lui CM, Wong M. Interleukin 1 beta – secreting cells in
inflamed gingival tissue of adult periodontitis patients. Cytokine
1999; 11: 626–33.
16. McCarty MF. Interleukin – 6 as a central mediator of cardiovascular
risk associated with chronic inflammation, smoking, diabetes
and visceral obesity: Down – regulation with essential fatty acids,
ethanol and pentoxifylline. Med Hypotheses 1999; 52: 465–477.
17. Mendall MA, Patel P, Asante M. Relation of serum cytokine concentrations
to cardiovascular risk factors and coronary disease.
Heart 1997; 78: 273–7.
18. Ioi H, Nakata S, Nakasima A, Counts AL, Nanda RS. Changes in
tooth position in humans in relation to arterial blood pressure.
Arch Oral Biol 2002; 47: 219–26.
19. Devereux RB, Roman MJ. Hypertensive cardiac hypertrophy:
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Diagnosis and Management. 2nd ed. New York: Raven
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20. Purienė A, Matulienė D, Ivanauskaitė D. Periodonto ligos:
periodontologinis tyrimas, diagnozė, gydymo planavimas ir
prognozė. Vilnius; 2000, p. 36.
21. Babarskienė R, Bandzaitienė R, Benetis R, Braždžionytė J, ir kt.
Širdies ligos. – Kaunas; 2001. p. 332.
22. Vaškelytė J, Jurkevičius R, Ereminienė E, Janėnaitė J.
Echokardiografiniai matavimai. Kaunas; 2000. p. 5–7.
23. Katz J, Flugelman MY, Goldberg A, Heft M. Association between
periodontal pockets and elevated cholesterol and low density lipoprotein
cholesterol levels. J Periodontol 2002: 73: 494–500.
24. Slade GD, Offenbacher S, Beck JD, Heiss G, Pankow JS. Acutephase
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25. Beck JD, Pankow J, Tyroler HA, Offenbacher S. Dental infection
and atherosclerosis. Am Heart J 1999; 138: 528–33.
26. Loesche W, Karapetov F, Pohl C. Plasma lipid and blood glucose
levels in patients with destructive periodontal disease. J Clin
Periodontol 2000; 27: 537–41.
27. Krause S, Pohl A, Pohl C, Liebrenz A, Ruhling K, Losche W.
Increased generation of reactive oxygen species in mononuclear
blood cells from hypercholesterolemic patients. Thromb Res 1993;
71: 237–40.
28. Shapira L, Borinski R, Sela MN, Soskolne A. Superoxide formation
and chemiluminescence of peripheral polymorphonuclear leukocytes
in rapidly progressive periodontitis patients. J Clin
Periodontol 1991; 18: 44–8.
29. Cutler CW, Shinedeling EA, Nunn M. Association between periodontitis
and hyperlipidemia: Cause or effect? J Periodontol 1999;
70: 1429–34.
30. Morrison HJ, Ellison LF, Taylor GW. Periodontal disease and risk
of fatal coronary heart and cerebrovascular diseases. J Cardiovasc
Risk 1999; 6: 7–11.
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disease and coronary heart disease risk. JAMA 2000; 284: 1406
– 10.
32. Angeli F, Verdecchia P, Pellegrino C, Pellegrino RG, Pellegrino G,
Prosciutti L, et al. Association between periodontal disease and left
ventricle mass in essential hypertension. Hypertension 2003; 41:
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SCIENTIFIC ARTICLES G. Valentaviciene et al.
CONCLUSIONS
1. The concentration of total cholesterol, triglycerides,
HDL, and LDL in blood serum did not differ significantly
in people (either males or females) with healthy periodontium,
gingivitis, or periodontitis.
2. The evaluation of the association of the LV mass
index with the CPITN index (in patients with hypertension)
yielded the following results: mean rank value in people
with healthy periodontium or with gingivitis (CPITN codes
0, 1, 2) was 48.3, and in people with periodontitis (CPITN
codes 3, 4) – 61.36 (p<0.05). The LV mass index elevated
with the increase in the degree of damage to periodontium
(the results were significant).

Reliability of ARCUSdigma (KaVo®) in diagnosing temporomandibular

SUMMARY
Objectives: to assess the sensitivity and specificity of ARCUSdigma in diagnosing temporomandibular
joint (TMJ) pathology (TMD).
Methods. 102 TMJs were exmined with ARCUSdigma and “Cadiax Diagnostic” electronic
axiography system. Free opening, free protrusion and mediotrusion were recorded with
both devices. Guided opening and guided protrusion were examined with “Cadiax Diagnostic”.
Using free opening and free protrusion diagnosis was established.
Results. Sensitivity of ARCUSdigma was found to be 84,21% and 92,86% for the right and
left TMJ respectively. Specificity – 93,75% and 95,65% for the right and left TMJ. The 95%
confidence interval for sensitivity and specificity was calculated.
Conclusions. Within the limitations of this study, ARCUSdigma appeared to be a valuable
supplement to clinical findings in diagnosing TMDs.
Key words: temporomandibular joint disorders; axiography; sensitivity; specificity.
*Institute of Dentistry, Faculty of Medicine, Vilnius University,
Lithuania
Giedre Kobs* – DDS, PhD
Asta Didziulyte* – clinical intern
Robertas Kirlys* – clinical intern
Mindaugas Stacevicius* – student
Address correspondence to Robertas Kirlys, Institute of Dentistry,
Zalgirio 115, Vilnius, Lithuania.
E-mail: rkirlys@gmail.com

INTRODUCTION
Internal derangement of the temporomandibular
joint (TMJ) has been defined as an abnormal positional
relationship of the disc relative to the mandibular
condyle, fossa and/or articular eminence, and is a
major cause of jaw pain, clicking and/or crepitation
as well as limitation of opening [1]. Systematic examination
of TMJ pathology is of utmost importance
[2] and the primary goal is to determine the status of
the stomatognathic system in the most non-invasive
way possible, then to document the situation and plan
a therapy, appropriate to the findings.
The increasingly progressive development of
medical diagnostic processes has opened new possibilities
in the compilation of findings for mandibular
disorders.
Magnetic-resonance-tomography (MRT) provides
a non-invasive procedure for imaging both the
osseous- and soft-tissue structures with a high degree
of resolution [3, 4]. Although MRT cannot be
considered a routine procedure, due to cost considerations,
it is still currently regarded as the best possible
diagnostic standard [5, 6, 7, 8].
Diverse instrumental registration techniques of
TMJ, based on electro-mechanic, opto-electronic, ultrasound
and magnetic principles also exist. According
to Meyer [9, 10], there are remote, near-TMJ
and TMJ-oriented methods to evaluate lower jaw
movements.
Computerized axiography is a noninvasive diagnostic
method, wich enables to record jaw movements
in three dimensions. After localizing the geometric
hinge axis, it is possible to record movements free
from distortion, wich are combined of rotation and
translation. However, despite refinements and expanded
possibilities for registration, the actual significance
of instrumental functional analysis in mandibular
joint diagnostics is still not conclusively clear. The
possibilities for error involved in extraoral registration
of functional movements have been discussed
elsewhere [10].
Electronic axiograph “Cadiax Diagnostic”, which
was considered as a reference method in this study,
utilizes exactly determined hinge axis - orbital reference
plane [11]. ARCUSdigma is a near-TMJ working
ultrasonic diagnostic device, that was put on the
market 3 years ago. ARCUSdigma is technically sim


4 8 Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 2
SCIENTIFIC ARTICLES G. Kobs al.
pler and cheaper than electronic
axiograph, however
there are no studies to support
its use in clinical work
as a diagnostic tool.
The American Academy
of Orofacial Pain (AAOP)
even discourages using instrumental
functional analysis
for the purpose of diagnosing
orofacial pain because
of lack of scientific evidence
[12].
On the other hand, the
German Society for Dentistry
and Orofacial Medicine attributes
at least as much
weight to instrumental functional
analysis as to clinical
findings [13, 14].
Having in mind the variance
of opinion in the scientific
literature, the objective
of this study was to assess
the ability of ARCUSdigma
to describe the kinematics of
diseased TMJs and determine
which movement patterns
is associated with a
clinically (or by other methods)
diagnosed joint pathology
[15].
MATERIAL AND
METHODS
From a group of patients
attending consultations at
Vilnius University Hospital
“Zalgirio clinics” 56 subjects
(8 males and 48 females)
were selected for this investigation.
The age of subjects
ranged from 15 to 76 years
old, with a mean age of 31,98.
This comprised 102 temporomandibular
joints.
All subjects underwent
computerized axiography using
“Cadiax Diagnostic” device
and also temporomandibular
joint examination using
ultrasonic device
ARCUSdigma (KaVo®) after
proper history taking and
assessment of clinical symptoms.
The data obtained using
“Cadiax Diagnostic” and
Fig. 1. Computerized axiography adjusted to head of patient
Fig. 3. A – left: Overlap of colour-coded axiograms of healthy joints; B – right: Opening/
closing cycle on the right joint shows anterior disk displacement with early reposition
(typical "figure eight") in the beginning of the movement
A
B



SCIENTIFIC ARTICLES
ARCUSdigma were independently
assessed by four
diagnosticians. “Cadiax Diagnostic”
was considered a
standard in this study.
Interclass correlation
coeficient (ICC) was calculated
to validate the use of
“Cadiax Diagnostic” as a
standard. Sensitivity and
specificity of ARCUSdigma
in diagnosing temporomandibular
joint pathology was
evaluated by k (kappa)
koefficient. Better visualisation
of results was done by
graphics.
Electronic axiography
diagnosis
The registration of TMJ
tracings was made with the
double face-bow “Cadiax
Diagnostic” system (Gamma,
Wien). Three-dimensionally
adjustable lower bow is used
to transmit hinge-axis movement
of the mandible to the
upper face bow (Fig 1).
In all cases the axiographic
findings were recorded
and assessed for both
joints. One of the folowing
diagnoses was made separately
for left and right temporomandibular
joints:
• no appreciable disease
• disk displacement
with early reposition
• disk displacement
with late reposition
• disk displacement
without reposition
• non classifiable
pathological change
Determination of the
jaw-tracking curvature degree
[11, 16]
For the evaluation of
pathological changes in the
following interpretation, the
curvature, especially from
opening/closing cycle and
free protrusion cycle (X-and
Z-axis), was a crucial factor.
Convex curves were defined
as definitely pathologic and
their characteristics were not
further analysed.
Fig. 2. Diagrammed determination of the of curvature coefficient on example of opening/closing
cycle. Legend: d – Distance between the beginning and the finish point of movement recording
(continuous red line); a – maximal deviation of the excursion or incursion curve from constructed
straight line between the beginning and the finish point (see double red arrow)
Fig. 4. A – left: Mediotrusive movement on the right joint shows typical "figure eight" creation
of the late disk reposition at the end of the movement. Red arrow shows the repositioning time;
B – right: Opening/closing cycle on the right joint is characterised as anteriorly convex, on the
left joint as straight line cycle. In both TMJ there is strong suspicion of DDWR
A
B
5 0 Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 2
SCIENTIFIC ARTICLES G. Kobs al.
In the case of a concave
curve it was necessary, to define
it clearly from straight
jaw-tracking in consideration
to the curvature degree. Figure
2 shows determination of
coefficient for the quantification
of the flexion performance
on opening/closing
cycle recording.
For evaluation of maximal
deviation the constructed
straight line (red line between
beginning and finish point of
the movement recording)
was displaced parallel downward
(increasing Z-value),
until it was tangent to the farthest
point of movement recording
(minor Z-value).
From the distance between
both straight lines (a) as well
as from the length between
beginning and finish point of
movement recording (d) we
get the curvature coefficient
K as follows:
In the present examination
we defined a limiting
value of K = 0,05 (that is
equivalent to a proportion of
).
In the case that the
curvature coefficient lies
around the limiting value
(0,04 £ K £ 0,06), no evidence
could be made due to
the curvature in terms of
pathological change. The
outcomes of this are the following
intervals:
K < 0,04
– straight line
0,04 £ K £ 0,06
– limit interval
K > 0,06
– curved track
Decision making in diagnosis
Due to the interpretation
of the jaw-tracking devices
the following suspecting diagnoses
were made:
a) “No appreciable
disease” described following
criteria (Figure 3: a) left):
K = a
d
= 1
20
a
d
Fig. 5. a) left: disk displacement without reduction (right joint): Opening/closing cycle underflows
mediotrusive und protrusive line (red circle); b) right: Both TMJs were signed with non-classifiable
pathological change
Fig. 6. Ultrasonic device ARCUSdigma adjusted to head of patient
A
B
Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 2 5 1
G. Kobs al. SCIENTIFIC ARTICLES
b) “Disk displacement with early reposition”
defined following criteria (Figure 3: b) right):
• typical „figure eight“ creation from excursive
and incursive cycles at the beginning area of coordinate
system;
• partial deviation of excursive from the
incursive line in the first 2 mm area of X- and Z-axis;
• negative value in the X-Axis at the and of
intrusion movement.
c) “Disk displacement with late reposition”
defined typical „figure eight“ creation in the terminal
phase of excursive und der incursive cycles (Figure
4: a) left).
• harmonically, reproducible, congruent cycles
with anterior concavity;
• mediotrusive line is slightly longer than protrusive
line and in the first 6-8 mm forms no Fischer
angle;
• free and managed Bennett movements are
ever positive and continuous;
• an average protrusive tracking length is about
8-10 mm, opening movement 10-12 mm and
mediotrusive movement 12-14 mm;
• In the first 8 mm protrusive-, opening-, and
mediotrusive cycles are normally coincident. Afterwards
the opening line runs usually above.
Fig. 7. "No appreciable disease" Fig. 8. "Disk displacement with early reposition"
Fig. 9. "Disk displacement without reposition" Fig. 10. "Non-classifiable pathological change"
5 2 Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 2
SCIENTIFIC ARTICLES G. Kobs al.
d) In the evaluation of diagnosis
„disk displacement without reposition“
the focal point was the interpretation
of the opening/closing cycles (Figure
4: b) right). In case of convex or straight
line cycles (curvature coefficient K <
0,04) disk displacement without reposition
(DDWR) was suspected diagnosis.
In case of a concave cycle with a
curvature coefficient K on a limit interval
(0,04 £ K £ 0,06), it was necessary
to check coincidence of the opening/closing
movement with those of the
mediotrusive and protrusive tracks. In
case of the opening/closing cycle
underflowing the mediotrusive und protrusive
movements, it was typical characteristic
of disk displacement without
reduction (Figure 5: a) left).
The concave cycle (K > 0,06) was
characterized as physiological.
e) Cycles, where due to the interpretation
criteria no clear diagnosis could
be made, get the identification „nonclassifiable
pathological change“
(Figure 5: b) right). At this point it has to
be noted, that the most “struck disks“ hide
under that coding. The typical characteristics
of the cycles are limited, slightly
concave, congruent curves.
Diagnosis using ultrasonic device
ARCUSdigma
The registration of TMJ tracings was
also made with the ARCUSdigma ultrasonic
device (KaVo, Germany). Ultrasonic
sender and receiver parts are used.
First the position of the upper jaw is recorded.
To register the lower jaw movements,
the sender is fixed on the vestibular
surfaces of lower anteriors with a
paraocclusal aid (Fig. 6).
In all cases both joints were examined
with ARCUSdigma. One of the
folowing diagnoses was made separately
for left and right temporomandibular joints:
• no appreciable disease
• disk displacement with early reposition
• disk displacement with late reposition
• disk displacement without reposition
• not classifiable pathological
change
Determination of the jaw-tracking
curvature degree
Since ARCUSdigma also provides
graphical representation of the condylar
movements in the form of curves, it was
Fig. 11. Distribution of diagnoses for right TMJ based on "Cadiax Diagnostic"
data
Fig. 12. Distribution of diagnoses for left TMJ based on "Cadiax Diagnostic"
data
Fig. 13. Distribution of diagnoses for right TMJ based on ARCUSdigma data
Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 2 5 3
G. Kobs al. SCIENTIFIC ARTICLES
and left temporomandibular joints respectively.
As it is seen from the graphs, dominant
diagnosis using data from “Cadiax
Diagnostic” was disk displacement with
early reposition. Pathology occuring in
right temporomandibular joint was more
comonly observed than in the left temporomandibular
joint.
The distribution of diagnoses made
with ARCUSdigma is shown in Figs. 13
and 14 for the right and left temporomandibular
joints respectively.
For the right TMJ ARCUSdigma
showed much less number of joints that
could be asssigned to “no appreciable
disease” group, only 32,14% compared
to 42,86% “no appreciable disease” joints
using “Cadiax Diagnostic” data. The
number of TMJs diagnosed with “disk
displacement with early reposition” was
comparable showing values of 41,07%
and 44,64% for “Cadiax Diagnostic” and
ARCUSdigma respectively. ARCUSdigma
was unable to detect joints having
disk displacement with late reposition.
The number of joints under “disk displacement
with no reposition” diagnosis was
higher with ARCUSdigma (14,29%) than
with “Cadiax Diagnostic” (12,5%). Diagnosis
of “non-classifiable pathological
condition” was also more often made
with ARCUSdigma (8,93%) than with
“Cadiax Diagnostic” (1,79%).
For the left TMJ the number of joints
with no appreciable pathology was equal
with both devices reaching 55,36%. Disk
displacement with early reposition was
more commonly diagnosed with
ARCUSdigma (26,79%) than with
“Cadiax Diagnostic” (23,21%). There was no “disk
displacement with late reposition” group using
ARCUSdigma on the left side. The absence of this
group was observed on the right side too. Using ultrasonic
device some disk displacements without reposition
were left undetected, the numbers reaching
16,07% and 10,71% with “Cadiax Diagnostic” and
ARCUSdigma respectively. However a diagnosis of
non-classifiable pathologic change could be reached
more often using ARCUSdigma (7,14%) than “Cadiax
Diagnostic” (1,79%).
Sensitivity and specificity values (including 95%
confidence intervals) of ARCUSdigma were calculated,
equivalence of two diagnostic devices was
evaluated by k (kappa) coeficient. The results are
shown in Fig.15.
High sensitivity and specificity values shown in
the graph above were for differentiating between “no
appreciable disease” and any pathologic condition in
possible to use the same curvature coefficient K and
similar criteria of decision making in diagnosis as described
above for “Cadiax Diagnostic”.
Decision making in diagnosis
Bellow typical examples of ARCUSdigma tracings
are shown for each diagnostic group:
“No appreciable disease” (Fig. 7),
“Disk displacement with early reposition”
(Fig. 8.),
“Disk displacement with late reposition”
There was not a single case with this diagnosis
working with ARCUSdigma.
“Disk displacement without reposition“(Fig. 9),
“Non-classifiable pathological change“(Fig. 10)
RESULTS
The distribution of diagnoses made with “Cadiax
Diagnostic” is shown in Figs. 11 and 12 for the right
Fig. 14. Distribution of diagnoses for left TMJ based on ARCUSdigma data
Fig. 15. Sensitivity, specificity values and kappa coeficient for ARCUSdigma
5 4 Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 2
SCIENTIFIC ARTICLES G. Kobs al.
the joint. High kappa coeficient of 79% and 88% for
the right and left temporomandibular joints respectively
were also calculated when differentiating
“healthy” from diseased. According to the kappa
coeficient equivalence of two diagnostic devices in
differentiating “healthy” from “diseased” TMJs was
deemed excellent.
DISCUSSION
Patients were selected for the study on the basis
of previous or present clinical symptoms, such as pain
in TMJ, clicking and/or crepitation, limited opening.
All subjects underwent computerized axiography using
“Cadiax Diagnostic” device and also temporomandibular
joint examination using ultrasonic device
ARCUSdigma after proper history taking and assessment
of clinical symptoms. A total number of 128
TMJs were examined. 102 pairs of TMJ tracings were
left for final examination. Each pair of tracings was
recorded during the same visit. First examination was
performed with “Cadiax Diagnostic”, second one with
ARCUSdigma. Tracings of 26 TMJs were discarded,
because patients had no clinical symptoms and instrumental
examination was performed only to obtain
data for fully adjustable articulators. Electronic
axiograph “Cadiax Diagnostic” can record more
movements than ARCUSdigma (including speech,
bruxing, MPI and guided movements), so only the
movements that both devices can record were chosen.
Calibration of four examiners was performed
using tracings of 40 TMJs (29 diseased, 11 no appreciable
disease). Common percent of coincidence of
93% (kappa 81%, 82%, 83%, 83%) was found.
Electronic axiograph “Cadiax Diagnostic” is considered
a valuable and reliable tool to aid in making
diagnosis and comparable to MRI according to literature,
so it was chosen as a reference in this study.
In a study by Kobs G. [11] electronic axiograph was
compared to MRI, which has high sensitivity of 67-
100% according to autopsy studies. Sensitivity of
“Cadiax Diagnostic” was 75,8% and 80,7% for left
and right TMJ respectively and specificity 90,7% and
82,8% for left and right TMJ respectively. It is proven
that electronic axiography is better at differential diagnosis
of dynamic dysfunction than MRI [17, 18].
Interclass correlation was calculated to check the
reliability of “Cadiax diagnostic” data. The result approximately
being equal to 1, “Cadiax Diagnostic” was
considered reliable.
Writing this article we had only six studies [19,
20, 21, 22, 23, 24] available where ARCUSdigma was
used. In three of them the device was only used as
an adjunctive tool and was not a subject of study itself.
In other three studies ARCUSdigma was used
as an additional patient examination tool besides medical
and dental history taking, clinical examination and
radiological examination. However in none of those
studies available to us sensitivity and specificity of
the device was determined. Also the reliability of
ARCUSdigma data was not determined using autopsy
or MRI data, which best represent joint anatomy. The
only study were reliability of ARCUSdigma data was
evaluated was performed not in clinical setting but
using predetermined values on articulators that were
measured with ARCUSdigma.
Same measurements can be performed using
both devices. Hinge axis – orbital reference plane is
used by “Cadiax Diagnostic”and camper horizontal
by ARCUSdigma. However it does not affect the
diagnosis.
ARCUSdigma was shown to be highly specific
and sensitive in differentiating between healthy and
diseased joints, however it performed worse when
used for differential diagnosis. These results conform
with Kiss G. et al. [19], who conclude that
ARCUSdigma is a good additional tool to examine
patients with TMJ dysfunction however it cannot replace
ordinary diagnostic methods, and with Kobs G.,
Bernhardt O., Meyer G. [25].
Piehslinger [26] and Gsellmann et al. [27] see a
special significance for axiography in the visual presentation
of dysfunctional dynamics and the strength
of MRT in the diagnosis of morphologic alterations.
They suggest combining the two methods, in order to
obtain a comprehensive evaluation of functional disorders
in the stomatognathic system
However the results presented offer some contradictions
to Lückerath et al. [28], Rammelsberg et
al. [29] and Rozencweig [30], who were the first to
show that tentative diagnoses, based on axiography
often did not correspond with findings from MRT.
Also, Bumann and Groot-Landeweer [31] could determine
correspondence between the two methods
in only 42% of the cases, whereby posterior discus
displacement and discus adhesions did not correspond
in any of the cases studied. Anterior discus dislocation
without repositioning was correctly diagnosed in
43% of the cases and non-pathologic findings were
correctly diagnosed in 35% of the cases.
Mohl et al. [32] and Türp [33] also doubted the
diagnostic value of mandibular movement registration
(because of the contradictory data in the literature).
Lund et al. [34] pointed out, that registrations of
active mandibular joint movements, irregardless of the
device, were so non-specific, that neither the registration,
nor the attempt at interpreting the tracks, was
meaningful for differential therapy. His opinion was
that these systems could still be useful, however, for
scientific problem-solving in isolated cases.
CONCLUSION
Ultrasonic axiograph registrations of mandibular
movements, in the framework of instrumental functional
diagnostics of the masticatory organ, appeared
to be a valuable supplement to clinical findings. HowStomatologija,
Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 2 5 5



Stomatologija, Baltic Dental and Maxillofacial Journal, 2007, Vol. 9, No. 2 5 5
G. Kobs al. SCIENTIFIC ARTICLES
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Received: 17 04 2007
Accepted for publishing: 17 07 2007
ever it should not be solely relied on in making differential
diagnosis and the direct assessment of
axiography tracks should be concerned less with
wanting to obtain definite indications whether the
patient being examined is functionally healthy or sick,
but rather with determining which movement pattern
is associated with a clinically (or by other methods)
diagnosed joint pathology [24].