The most common genetic syndromes and associated anomalies in Latvian patients with cleft lip with or without palate

1 over 700 newborns every year is born with cleft lip with/or without palate, in 30% of cases there is a certain genetic mechanism underlying development of disease: chromosomal anomalies, monogenic diseases, exposure to teratogens or in utero disruptive mechanisms.
The objective of our study is to describe the most common genetic syndromes and associated anomalies in patients with CL/CP in Latvia.
Materials and methods
Study material was medical records obtained from Riga Cleft Lip and Palate Centre Registry in a time period of 1980 till 2005. There was analyzed information about patients with identified genetic syndromes and associated anomalies.